The Run-and-Shoot Offense: (In Lay-Mans terms)THe splits for the linemen are larger than they normally are in the spread, to create passing lanes quicker for the QB. Though the Run-and-Shoot is run prodominantly out shotgun like the spread, the major difference in the Run-and-Shoot is that the WR's make their own reads on the defense and adjust their routes accordingly. The QB has to be able to recognize the read the WR is making and throw the ball to the adjusted route. The Spread: Is basically an offense that's run out of shotgun where a tight-end is utilized, where as the run-and-shoot tends to cut out the TE position. As well the blocking assignments are called out by the center and the QB has to make any adjustments to the play call himself (audibles) or in Akron's case they look to the sidelines (similar to many high school teams) for the checks. Also there are only rare occaisions where the reciever has the ability to make an adjustment on his route during the play. The spread is a far more simple offense than the run-and-shoot, which is why you'll never see the spread in the NFL and you'll never see the run-and-shoot used in high school.