Over/Under48.5 total points (DraftKings)
Key Storylines• This is the first ever meeting between the two programs. • Akron has struggled historically in season‑openers against FBS opponents (13 straight losses), but they hold a 1‑0 record vs. Mountain‑West teams. • Wyoming hopes to rebound from a down year and prove they can compete despite a major transfer exodus after 2022.